Human Organs-on-Chips Market Size, Share, Growth, and Industry Analysis, By Type (Liver-on-a-chip, Kidney-on-a-chip, Intestine-on-a-chip, Lung-on-a-chip & Heart-on-a-chip), By Application (Academic & Research Institutes & Cosmetics Industry) and Regional Forecast to 2032

Updated On: 02 September 2024

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HUMAN ORGANS-ON-CHIPS MARKET REPORT OVERVIEW

The global Human Organs-on-Chips Market Size was USD 80.9 million in 2023 and the market is projected to touch USD 347.08 million by 2032, exhibiting a CAGR of 15.68% during the forecast period.

Currently, the Human Organs-on-Chips market is one of the most promising areas in the biomedical industry, presenting devices that mimic human organs’ complexity. Thus, these chips offer a more precise, moral, and beneficial method of cell culture as well as animal culture, enhancing superior research in the production of drugs, the diagnosis of diseases, and even tailored medicine. By mimicking the physiological response of human tissues and organs, organs-on-chips improve the predictiveness of preclinical studies. This emerging phenomenon is applying tremendous pressure on the healthcare and pharmacological industries, considerably transforming the human biology knowledge base and therapeutic solutions map.

COVID-19 Impact: Market Growth During Pandemic Due To COVID-19 Research Needs

The global COVID-19 pandemic has been unprecedented and staggering, with the market experiencing higher-than-anticipated demand across all regions compared to pre-pandemic levels. The sudden market growth reflected by the rise in CAGR is attributable to market’s growth and demand returning to pre-pandemic levels.

The COVID-19 pandemic expanded the Human Organs-on-Chips market at a higher rate since scientists leaned toward more effective techniques to analyze the contagion and find remedial measures quickly. These chips offered essential information on the viruses and their effects on host cells and on drugs without using animals, cutting down on the time it took for research. The realization of the importance of searching for effective antiviral therapeutics and vaccines during this period promoted the application and investment in this type of technology in biomedical research. Thus, the pandemic played a crucial role for Human Organs-on-Chips employees and people in general in revealing perspectives on improved healthcare and more effective research.

LATEST TRENDS

"AI and ML adoption drives market growth in organs-on-chips technology"

The current trend worth noting in the human organs-on-chips market is the adoption of AI and ML for improving data analytics and modeling processes. Artificial intelligence algorithms are applied to analyze large amounts of biological data, which is obtained by experiments using organ-on-chip technology, in order to support the development of new drugs and individualized medicine. Some trends encompass the capacity of AI processing to enhance experimental designs, provide improved drug response forecasts, and therefore advance therapeutic solutions’ development.

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SEGMENTATION

By Type

Based on type the market can be categorized into Liver-on-a-chip, Kidney-on-a-chip, Intestine-on-a-chip, Lung-on-a-chip & Heart-on-a-chip.

Liver-on-a-chip: On a chip, the liver mimics essential metabolic processes of the liver, and this enables physicians to examine how drugs get metabolized and the level of toxicity. These chips imitate the liver's responses to drugs and toxins more than the traditional approaches to performing liver-based analysis, therefore making them efficient tools to determine hepatic metabolism and drug diseases.

Kidney-on-a-chip: Kidney-on-chips act as the functioning kidney and are utilized in filtration, reabsorption, secretion processes, nephrotoxicity, and kidney disorder studies. These models imitate the complexity of the function of the kidney and offer data relating to drug nephrotoxicity—the process of either establishing or developing a brand new kidney remedy.

Intestine-on-a-chip: Intestine on a chip mimics the human intestines and also involves functional functions such as movement of the tool known as peristalsis and the motor function of taking in nutrients. These models are crucial for the investigation of GI disorders, the application of drugs, and their assimilation with the outcomes in association with drug microbiome interphase communications; they provide a much superior comprehension over cell culture models.

Lung-on-a-chip: Microphysiological systems, or lung-on-a-chip, model the human lungs, including the airways, gas exchange, breathing, and immunological response. These models are employed in asthma, pulmonary infections, and other lung diseases so researchers can examine how efficient drugs are in treating the disease and the degree of toxicity they possess, as well as experiment on the disease in a more natural setting.

Heart-on-a-chip: These silicon hearts mirror a cardiac extra-cellular matrix, the genetic wiring diagram, contractility, electrical conductivity, and pharmacological response. These microfluidic devices let the researchers study heart diseases, cardiotoxicity, and the ways of cardiac regeneration, helping them comprehend the mechanisms of cardiac functioning and develop personalized approaches to cardiac treatment.

By Application

Based on application the market can be categorized into Academic & Research Institutes & Cosmetics Industry.

Academic and Research Institutes: The representatives of academic and research institutions use human organs-on-chips to analyze the pathophysiology of diseases, drug efficacy, and other biological phenomena in controlled conditions. These advanced models allow the researcher to perform studies that are more physiological than those with cell cultures and animal models. This technology is fundamental for enhancing the speed of discoveries in biomedical research and moving findings to practice.

Cosmetics Industry: The beauty products market consumers human organs on chips to determine the effectiveness and safety of the beauty products without using animals for testing. These devices model human skin and other tissues, which facilitates the assessment of more real potential irritants and allergens. This is not only beneficial for the consumer but also maintains the ethicality and legal compliance of the product tested.

DRIVING FACTORS

"Organs-on-chips' precision drives market growth in biomedical research advancements"

The key factor of the Human Organs-on-chips market growth is the progress in biomedical research which never seems to cease, hence the constant demand for better and more precise models in the understanding of the human body and illnesses. Organs-on-chips better imitate human organ performance in contrast to other research models, such as cell cultures or animal models; therefore, the transition between preclinical and clinical phases will be shorter. This capability will prove useful in the improvement of the discovery and development phases of pharmaceuticals.

"Ethical issues and regulations boost organs-on-chips market growth"

Rising ethical issues and legal requirements to minimize the use of animals foster the demand for human organs-on-chips. These gadgets offer a more sensible and moral solution towards analyzing the efficiency of those drugs and their effect on animals, with respect to the global campaign to decrease animal use in biomedical investigations. Various government organizations gradually acknowledge the effectiveness and applications of organs-on-chips in toxicity testing and drug discovery, which in turn boosts market growth.

RESTRAINING FACTOR

"High complexity and costs limit market growth of organs-on-chips"

The challenge of complexity and cost in creating as well as sustaining the pendants of microfluidic human organs on chops is, in essence, a restraint on the market in question. Organ-on-chips are generally created by microengineering technologies and specific materials that may be costly and demanding to use. Also, increasing the production level to match the commercial requirement for the keyboard and maintaining the same level of performance adds to the issues, which may hinder its adoption in numerous research institutions and the pharmaceutical industries.

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HUMAN ORGANS-ON-CHIPS MARKET REGIONAL INSIGHTS

The market is primarily segregated into Europe, Latin America, Asia Pacific, North America, and Middle East & Africa.

"North America's robust research and investments drive market growth"

North America holds the largest Human Organs-on-Chips Market Share mainly due to the extensive research facilities of developed universities and biotechnology industries. The region enjoys the right investment in biomedical research and development to advance on new technologies such as organs-on-chips. Furthermore, it can be noted that adequate and effective cooperation with other research institutions, companies, and governmental bodies facilitates the commercialization and subsequent approval of these devices and thus confirms North America’s role as a leading region in this sphere.

KEY INDUSTRY PLAYERS

"Increased investments and partnerships drive market growth of organs-on-chips"

Manufacturers are raising investments in the Human Organs-on-Chips, the impact of which enables the development of the devices and increases the market’s importance by creating more functions for the tools. These have partnerships in penetration with universities and pharmaceuticals, as well as in commercialization. Besides, such players are concerned with maintaining regulatory standards for the efficient functioning of organs on chips along with research and development for standardization processes relating to the dependability and replicability of these technologies to make them more acceptable and thus infiltrate the market more effectively.

List of Market Players Profiled

• Kirkstall (U.K.)
• Micronit (Netherlands)
• CN Bio Innovations (U.K.)
• Mimetas (Netherlands)
• Emulate (U.S.)

INDUSTRIAL DEVELOPMENT

May 2024: Emulate Inc., a leading developer in the Human Organs-on-Chips Market launched the "Gut-on-a-Chip". This microfluidic device specifically models the human intestinal tract and offers several advancements. Firstly, it incorporates human intestinal cells, providing a more human-relevant setting for studying gut functions compared to traditional methods. Secondly, the chip allows the inclusion of gut microbes, enabling research on the gut microbiome's influence on human health. Finally, these features hold promise for the drug discovery field, potentially leading to the development of more effective treatments for gut-related diseases.

REPORT COVERAGE

This report is based on historical analysis and forecast calculation that aims to help readers get a comprehensive understanding of the global Human Organs-on-Chips Market from multiple angles, which also provides sufficient support to readers’ strategy and decision-making. Also, this study comprises a comprehensive analysis of SWOT and provides insights for future developments within the market. It examines varied factors that contribute to the growth of the market by discovering the dynamic categories and potential areas of innovation whose applications may influence its trajectory in the upcoming years. This analysis encompasses both recent trends and historical turning points into consideration, providing a holistic understanding of the market’s competitors and identifying capable areas for growth.

This research report examines the segmentation of the market by using both quantitative and qualitative methods to provide a thorough analysis that also evaluates the influence of strategic and financial perspectives on the market. Additionally, the report's regional assessments consider the dominant supply and demand forces that impact market growth. The competitive landscape is detailed meticulously, including shares of significant market competitors. The report incorporates unconventional research techniques, methodologies and key strategies tailored for the anticipated frame of time. Overall, it offers valuable and comprehensive insights into the market dynamics professionally and understandably.